Description
What is 5-Amino-1MQ?
5-Amino-1MQ (5-Amino-1-methylquinolinium) is a small molecule — not a peptide — that has gained attention for its novel metabolic mechanism. It works by selectively blocking NNMT (Nicotinamide N-Methyltransferase), an enzyme found primarily in fat cells and the liver.
When NNMT is overactive, it depletes key metabolic molecules and reduces NAD+ availability — both associated with increased fat storage and metabolic dysfunction. By inhibiting NNMT, 5-Amino-1MQ essentially removes a metabolic brake, allowing the body to burn fat more efficiently and maintain healthier NAD+ levels.
What Researchers Are Exploring
Fat Loss & Metabolism Research shows inhibiting NNMT reduces fat cell size and decreases overall fat mass — without affecting food intake. The compound shifts fat cells from a storage state to a more metabolically active state.
NAD+ & Cellular Energy By blocking NNMT, 5-Amino-1MQ increases intracellular NAD+ levels — connecting its metabolic effects to broader cellular health and longevity research.
Body Composition Studies suggest NNMT inhibition may support lean body composition by reducing fat while preserving muscle.
Worth Noting 5-Amino-1MQ targets an enzyme in fat cells rather than working through hormonal, receptor, or neurotransmitter pathways — making it mechanistically different from every other metabolic compound available.
For research use only. Not intended for human consumption. Not approved by the FDA or TGA.
